UEMS Medical Specialty

Geriatrics & Longevity Medicine — Page 2

Dossiers covering senolytic compounds, NAD⁺ precursor supplementation, cellular senescence, and evidence-based longevity medicine formulations.

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dossiers

Cerebral Bioenergetics & Neuro-Metabolic Rescue

Ketogenic Diet-Specified Interventions in Neurodegenerative Disease Mechanisms

Developing a formulation that achieves consistent and measurable ketosis while optimizing bioavailability and tolerability in neurodegenerative conditions is a key challenge.

Alzheimer DiseaseParkinson DiseaseNeurodegenerative DiseasesNeuroinflammation

Intracellular Defense & IV-Alternatives

Oxidative Stress Mitigation in Nutraceutical Stability: Packaging and Formulation Strategies

Nutraceutical dosage forms face significant degradation due to oxidative stress, driven by moisture, oxygen, and light. This presents a challenge for maintaining stability across supply-chain conditions and long shelf lives.

AgingProbioticsDrug Stability

Cellular Longevity & Senolytics

Synergistic Modulation of Cellular Senescence Biomarkers by Target-Specific Nutraceutical Matrices

Developing a nutraceutical matrix that precisely modulates senescence-related biomarkers requires integrating senolytic activity, SASP suppression, and mitochondrial restoration within a single formulation while ensuring in vitro reproducibility and scalability.

SenotherapeuticsCellular SenescenceNADInflammation

Cellular Longevity & Senolytics

Comparative Pharmacokinetics and Cellular Bioaccessibility of Senolytic Agents: Impact of Polymeric-Matrix Encapsulation

Orally administered senolytic compounds often suffer from poor pharmacokinetics, including low and variable bioavailability, rapid metabolism, pH-dependent dissolution, and limited cellular bioaccessibility.

SenotherapeuticsNanoparticlesDrug CompoundingBiological Availability

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